Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Aug 1;7:6997. doi: 10.1038/s41598-017-07460-w

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Effects of AM251 on the activity of IC neurons. (A) Typical recordings of an IC neuron under an oddball stimulation paradigm before (control), during (AM251), and after (recovery) an i.v. application of AM251. (For this neuron, the standard frequency was 8574 Hz, and the deviant frequency was 10472 Hz.) The insets show the PSTH of the responses. (B) Scatter plot of the CSI in control condition versus AM251 application. (C) Bootstrapping analysis showing that AM251 produced significant changes in the CSI only in 7/49 neurons. (D) Bars represent the average of the CSI values ± SE in control condition, AM251 application and recovery. (E) Scatter plot of the firing rate showing the spike count for deviant and standard frequencies in control condition versus AM251 application. (F) Bars show the percent change in the spike count averaged for deviant and standard stimuli by AM251 application. There is a tendency for a decrease in the firing rate for both frequencies. Vertical bars represent the % change ± SE.