Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Aug 1;7:6985. doi: 10.1038/s41598-017-07622-w

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Tubular structure formation in ovarian cancer cell-derived spheroids. (a) Cancer spheres were generated from parental SKOV3 and HEY cells (noted as “before seeding”) and individual spheres seeded onto matrigel. At day 1 the cells grew principally within the spheres structure before spreading out to cover the dish at day 3 and forming clear tubular structures at day 4 in both cell lines. Magnification: 4×. Scalebar: 200 μm. (b) PAS staining (left) and microinjection (middle and right) of a 4 day-old spheres initiated 3D-cultures on matrigel. Arrowheads line the borders of microinjected structure. Magnification: 10×. Scalebar: 100 μm.