Table 3. Subgroup analysis by ethnicity for OGG1 rs1052133, XRCC1 rs25489, and ERCC1 rs11615.
| Pathway | Gene | rs number | Wt allele |
European per allele |
Chinese per allele |
P value | ||
|---|---|---|---|---|---|---|---|---|
| OR | 95% CI | OR | 95% CI | |||||
| BER | OGG1 | rs1052133 | C | 1.11 | 1.00–1.23 | 1.03 | 0.93–1.14 | 0.32 |
| XRCC1 | rs25489 | G | 1.04 | 0.94–1.15 | 0.92 | 0.82–1.02 | 0.10 | |
| NER | ERCC1 | rs11615 | C | 1.11 | 0.96–1.30 | 1.13 | 0.97–1.32 | 0.90 |
BER, base excision repair; CI, confidence interval; NER, nucleotide excision repair; OR, odds ratio; Wt, wild type.
European patients were compared with controls. Chinese patients were compared with controls. A χ2-test to detect subgroup difference found nonsignificant P values.