Table 3.

Selected loss-of-function murine cardiac connexin models

Gene	Genotype	Phenotypes	Reference Nos.
Cx30.2	Cx30.2−/−	Reduced PQ interval	590–592
Cx40	Cx40−/−	Prolonged ECG P-wave; prolonged PQ intervals; supraventricular arrhythmias; normal ventricular conduction	57, 176, 396, 573, 1026, 1065, 1172, 1191
Cx43	Cx43+/−	Normal P wave durations; reduced ventricular conduction velocities; homozygote lethal	296, 937, 1132
	Cx43- (inducible)		286
	Cx43- (cardiac specific)		389
Cx45	Cx45−/−	Normal AV conduction, i.e., normal PQ and QRS duration	596, 602
	Cx45−/− (cardiac specific)		326