FIGURE 8.

MRI findings in limbic encephalitis compared with the surgical resection of the hippocampi of “Henry M.” MRI from a patient with autoimmune limbic encephalitis (A); the arrows point to the hippocampi which show increased signal intensity in fluid-attenuated inversion recovery (FLAIR) sequences, representing areas of inflammation and edema. The drawing in B shows in green the area of both hippocampi that was removed from patient “Henry M,” who was extensively studied over many years by Dr. Brenda Milner and whose findings were fundamental to understand the role of hippocampus in memory formation (281).