Table 1. Promoter analysis of major antiviral response elements in human viperin, IFIT1 and CXCL10 genes was performed by identification of promoter regions with ‘Promoser’ and potential transcription factor-binding sites using MatInspector (Genomatix Suite).
| Promoter element; Gene name | ISRE |
IRF |
NFkB | ||||
|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 7 | 8 | |||
| Viperin | 2 | – | – | – | 1 | – | 1 |
| IFIT1 | 3 | 1 | 2 | 1 | 1 | – | 1 |
| CXCL10 | – | 1 | 1 | – | – | 1 | 4 |
Abbreviations: IRF, interferon regulatory factor; ISRE, interferon-stimulated response element; NFkB, nuclear factor κB.