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. 2017 Aug 2;9:55. doi: 10.1186/s13195-017-0281-7

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Whole-brain group differences in RSI and DTI metrics. Contrast maps show voxels with significantly lower ND or FA, and greater IF or MD, for MCI versus HC and for AD versus HC (p < 0.01, FWE cluster corrected). AD Alzheimer’s disease, FA fractional anisotropy, HC healthy controls, IF isotropic free water diffusion, MCI mild cognitive impairment, MD mean diffusivity