Table 4.

Multiple linear and logistic regression of SUA level for MMSE score and MCI prevalence

	SUA level (continuous)		SUA level (quartiles by gender)
MMSE score	β(95% CI)	P	Q1	Q2 β(95% CI)	Q3 β(95% CI)	Q4 β(95% CI)	P trend
Participants with hyperuricemia
Male	−0.03(−0.56–0.39)	0.721	1.00(Ref)	0.97(0.66–1.43)	0.92(0.58–1.26)	0.99(0.87–1.13)	0.544
Female	−0.01(−0.43–0.37)	0.882	1.00(Ref)	1.07(0.80–1.27)	1.05(0.78–1.31)	1.00(0.92–1.18)	0.922
Participants without hyperuricemia
Male	0.14(0.04–0.42)	0.048	1.00(Ref)	1.01(0.69–1.48)	1.50(0.85–2.64)	1.65(1.12–2.43)	0.027
Female	0.28(0.02–0.53)	0.037	1.00(Ref)	1.53(1.00–2.33)	1.84(1.27–2.90)	1.92(1.02–3.35)	0.017
Prevalence of MCI	OR (95% CI)	P	Q1	Q2 OR (95% CI)	Q3 OR (95% CI)	Q4 OR (95% CI)	P trend
Participants with hyperuricemia
Male	1.06(0.47–1.64)	0.126	1.00(Ref)	0.48(0.10–2.33)	0.54(0.12–2.40)	0.10(0.01–0.97)	0.256
Female	1.02(0.67–1.56)	0.915	1.00(Ref)	0.59(0.18–1.90)	0.32(0.08–1.23)	1.08(0.36–3.20)	0.246
Participants without hyperuricemia
Male	0.82(0.68–0.99)	0.047	1.00(Ref)	0.95(0.50–1.78)	0.91(0.49–1.70)	0.72(0.38–1.36)	0.025
Female	0.80(0.65–0.97)	0.034	1.00(Ref)	0.87(0.45–1.70)	0.72(0.44–1.77)	0.64(0.39–1.06)	0.008

Adjusted for age, education, marital status, BMI, current smoking, current drinking, physical activity ≥ 0.5 h/day, family history of dementia, hypertension, cerebral vascular disease and diabetes