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. 2017 Jun 23;17(7):1484. doi: 10.3390/s17071484

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© 2017 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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(A) Localized surface plasmon resonance (LSPR) peak shifts as a function of time during supported lipid bilayer (SLB) fabrication on silica-coated nanodisk arrays using zwitterionic DOPC and positively charged DOPC:DOEPC 70:30 vesicles. Inset shows the characteristic kink in the LSPR response, which is associated with the onset of vesicle rupture at a critical surface coverage of adsorbed vesicles; (B) LSPR peak shifts as a function of ΔRIU in glycerol/water mixtures. Linear fits show bulk refractive index sensitivities (nm/RIU) of bare silica-coated nanodisk arrays as well as silica-coated nanodisk arrays coated with DOPC and DOPC:DOEPC 70:30 SLBs.