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. 2017 Aug;58(10):3862–3870. doi: 10.1167/iovs.17-21796

Figure 1.

Figure 1

Dietary ω-3 LCPUFA versus ω-6 LCPUFA suppressed laser-induced CNV. Eight-week-old C57BL/6J (WT) mice were fed ω-3 or ω-6 LCPUFA-enriched diets starting 1 week before and continuing until 1 week after laser-induced CNV (day 0). At day 7, choroidal neovessels were examined. (A) Representative neovessel lectin-stained (red) choroidal whole-mounts. The brackets in the top panel are shown at the bottom. (B) Significantly reduced lesion areas were found in ω-3 versus ω-6 LCPUFA-fed retinas. n = 12 to 14 mice per group. Unpaired t-test. Arrow (top): optic nerve head. Scale bar: 200 μm (top); 50 μm (bottom).