Fig. 4. (a) Luminescence response of the system in the presence of helicase, S1, Endo, DpnI, ExoI, EcoRI, RNase, DNase and SSB. (b) Luminescence spectra of the 9/G-quadruplex system in a reaction system containing 0.5% (v/v) cell extract in response to various concentrations of helicase: 0, 0.18, 0.36, 0.45, 0.54, 0.72, and 0.9 μM. (c) Relative luminescence intensities of the system in the presence of increasing concentrations of ciprofloxacin: 0, 1, 2.5, 5, 10, and 20 μM. (d) Emission spectra of complex 9 in the absence and presence of 20 μM ciprofloxacin. (e) Relative luminescence response of the 9/G-quadruplex ensemble upon the addition of 20 μM ciprofloxacin. (f) Luminescence response of the system treated with 0.8 μM helicase and 10 μM of suramin, TBBT and ciprofloxacin.
