Table 3.
Risk factors: multivariable analysis | All cases | Mild cases only | Severe cases only | |
---|---|---|---|---|
Odds ratio (95% CI) |
Odds ratio (95% CI) | Odds ratio (95% CI) |
||
Chronic hypertension | Unadjusted | 4.8 (2.8–8.3) | 3.3 (1.6–6.5) | 8.6 (3.4–21.7) |
Adjusted | 4.2 (2.4–7.4) | 3.0 (1.4–6.3) | 8.4 (3.1–22.5) | |
Infection present on admission | Unadjusted | 2.8 (1.6–4.7) | 4.3 (1.7–10.6) | 2.1 (1.1–4.1) |
Adjusted | 2.6 (1.4–4.6) | 4.5 (1.6–12.6) | 1.9* (0.9–4.0) | |
Prothrombotic statea | Unadjusted | 3.6 (2.0–6.5) | n/a | 6.1 (3.1–12.2) |
Adjusted | 2.9 (1.3–6.4) | n/a | 6.6 (2.5–17.5) | |
Coagulopathyb | Unadjusted | 2.8 1.7–4.7 | n/a | 3.0 (1.7–5.4) |
Adjusted | 1.5 (0.8–3.1) | n/a | 1.3 (0.5–2.9) | |
Obesity | Unadjusted | n/a | 9.0 (1.8–44.6) | n/a |
Adjusted | n/a | 4.9 (0.9–26.5) | n/a | |
Heart diseasec | Unadjusted | 4.5 (1.3–15.9) | n/a | 3.8 (1.0–14.0) |
Adjusted | 2.1 0.5–9.9 | n/a | 1.0 (0.2–5.4) | |
Migraine | Unadjusted | 3.6 (1.1–11.8) | n/a | n/a |
Adjusted | 3.6 (0.9–14.5) | n/a | n/a | |
Multiple gestation | Unadjusted | 0.3 (0.1–0.8) | n/a | 0.3 (0.1–0.9) |
Adjusted | 0.2 (0.1–0.9) | n/a | 0.2 (0.04–0.7) | |
Multigravida | Unadjusted | 0.5 (0.3–0.7) | n/a | 0.3 (0.2–0.5) |
Adjusted | 0.6 (0.4–0.9) | n/a | 0.3 (0.2–0.6) |
Includes primary hypercoagulable state, history of deep vein thrombosis or pulmonary embolism, systemic lupus erythematosis, sickle cell disease.
Includes bleeding diatheses and thrombocytopenia.
Includes congenital, valvular, and ischemic heart disease, and congestive heart failure.
See Supplemental Table II for complete details of diagnostic codes.