Figure 4.

The s120S protein levels of patients with COPD. A, The s120S protein level in relation to frequent exacerbations of COPD. Relationship between the s120S protein level and (B) FEV₁ % predicted, (C) 6MWD, (D) MRC dyspnea score, and (E) s120S protein levels in patients with COPD with different BODE index. F, Time dependency of SIRT1 in cell-culture supernatant from BEAS-2B cells (B2B) or (G) A549 cells. 6MWD = 6-min walking distance; BODE = BMI, airflow obstruction, dyspnea, and exercise capacity. See Figure 1 legend for expansion of other abbreviations.