Table 2. Dermoscopic Features Associated With Risk of Incorrect Diagnosis of Melanoma as Seborrheic Keratosis and With Correct Diagnosis of SK–like Melanoma .
| Feature | Dermoscopically Non–SK-like MM, No. (%) (n = 110 [82.1%]) |
Dermoscopically SK-like MM, No. (%) (n = 24 [17.9%]) |
Risk of Diagnosing MM as SK by Dermoscopy, OR (95% CI) |
P Value |
|---|---|---|---|---|
| Dermoscopic Features Associated With Risk of Incorrect Diagnosis | ||||
| Hairpin vessels | 1 (0.9) | 6 (25) | 36.3 (4.1-319.8) | <.001 |
| Fingerprint-like areas | 1 (0.9) | 3 (12.5) | 15.6 (1.5-157) | .02 |
| White halo surrounding vessels | 3 (2.7) | 6 (25) | 11.9 (2.7-51.9) | <.001 |
| Cerebriform-like pattern | 2 (1.8) | 4 (16.7) | 10.8 (1.8-62.9) | .01 |
| Network-like structures | 5 (4.5) | 7 (29.2) | 8.6 (2.5-30.4) | <.001 |
| Fissures and ridges | 7 (6.4) | 8 (33.3) | 7.3 (2.3-23.1) | .001 |
| Scale and hyperkeratosis surface | 28 (25.5) | 17 (70.8) | 7.1 (2.6-18.9) | <.001 |
| Comedo-like openings | 26 (23.6) | 15 (62.5) | 5.4 (2.1-13.7) | <.001 |
| Yellowish keratin | 27 (24.5) | 15 (62.5) | 5.1 (2.0-13.0) | <.001 |
| Milia-like cysts | 21 (19.1) | 9 (37.5) | 2.6 (0.98-6.6) | .05 |
| Dermoscopic Features Associated With Correct Diagnosis | ||||
| Pigment network | 73 (66.4) | 1 (4.2) | 0.02 (0.003-0.17) | <.001 |
| Pseudopods or streaks | 45 (40.9) | 2 (8.3) | 0.13 (0.3-0.59) | .002 |
| Blue-black sign | 41 (37.6) | 2 (8.3) | 0.15 (0.03-0.6) | .005 |
| Irregular globules and dots | 58 (52.7) | 6 (25) | 0.30 (0.1-0.8) | .01 |
| Blue-white veil (raised area) | 64 (58.2) | 8 (33.3) | 0.36 (0.14-0.91) | .03 |
| Atypical vessels | 50 (45.5) | 6 (25) | 0.3 (0.1-0.9) | .06 |
Abbreviations: MM, melanoma; OR, odds ratio; SK, seborrheic keratosis.