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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: Glia. 2017 Jun 15;65(9):1504–1520. doi: 10.1002/glia.23176

Figure 6. MDI is accelerated in brains of Alzheimer’s disease and autism patients.

Figure 6

MDI was quantified from gene expression data of patients with (a) Alzheimer’s disease (GSE5281, two-way ANOVA, Region p< 0.0001; Disease p < 0.0001) and (b) autism (GSE28521, two-way ANOVA, MDI * p < 0.05) and compared to controls as discussed above. For both, results remained significant after controlling for age-related and regional variability (p<0.05). (c) MDI was calculated using data from adult males and females (18y+, BrainSpan developmental dataset).