Extended Data Fig. 2. Mouse chromogranin B expression.

a-i, IHC staining shows no CgB reactivity in mouse GCs of immunised WT or Sanroque spleens and Peyer’s patches (n=3). j, IHC control staining for CgB in mouse pancreas islets. (a-j). Scale bar 100 μm. n=3 k, Relative mouse CHGB mRNA expression in different T cell subsets with adrenal gland as positive control. T cells were FACS sorted as follows: T_naïve (CD4⁺ CD44^lo CD25^-); T effector memory (T_EM, CD4⁺ CD44^hi CD25^- PD-1^-/lo CXCR5^-/lo); T_FH (CD4⁺ CD44^hi PD-1^hi CXCR5^hi); T_REG (CD4⁺ CD25⁺ CD44^int). GAPDH was used as housekeeping gene (n=3).