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Simplified kynurenine pathway of tryptophan metabolism. ACMSD: aminocarboxymuconate semialdehyde decarboxylase, IDO: indolamine-2,3-dioxygenase, KAT: kynurenine aminotransferase, KMO: kynurenine 3-monooxygenase or kynurenine 3-hydroxylase, KYNU: kynureninase.
