Table 4.

Multivariable linear regression output for the base and exploratory models. Incremental R² represents the amount of model variability explained by the sequential addition of variables from each domain.

Model	Variable domain	Standardized β coefficient	Incremental R2	Adjusted R2
Single-item global QOL				0.257***
Role functioning	EORTC	0.286***	0.132***
Future perspectives	BLM	0.106	0.025*
Average goal attainment	Goals	0.264**	0.086***
Average activity difficulty	Activity	−0.190*	0.034**
EORTC Global Health Status				0.515***
Fatigue	EORTC	−0.242**	0.495***
Social functioning	EORTC	0.127
Constipation	EORTC	−0.167**
Physical functioning	EORTC	0.178**
Role functioning	EORTC	0.188*
Future perspective	BLM	0.124*	0.021**
Average goal attainment	Goals	0.155*	0.022**
Mental health inventory score				0.464***
Emotional functioning	EORTC	0.457***	0.399***
Future perspective	BLM	0.255***	0.053***
Average goal attainment	Goals	0.158*	0.023*
Satisfaction with life scale				0.148***
Physical functioning	EORTC	0.235**	0.165***
Emotional functioning	EORTC	0.215**
Constipation	EORTC	−0.164*
Days engaged in activities outside of home				0.217***
Fatigue	EORTC	−0.258**	0.118***
Sexual functioning	BLM	−0.180*	0.073**
Future perspective	BLM	0.221**
Number goals	Goals	0.203**	0.029*
Proportion of activities that took too long	Activity	−0.158*	0.024*
Days of activities missed due to illness				0.298***
Role functioning	EORTC	−0.392***	0.251***
Social function	EORTC	−0.193*
Proportion of activities that took too long	Activity	0.297***	0.066***
Proportion of activities associated with discomfort	Activity	−0.187*

Significance level of variable entry

^*p<0.05

^**p<0.01

^***p<0.001

EORTC: European Organization for Research and Treatment of Cancer

BLM: BLM30 module

QOL: Quality of life