Table 2.
Formulations | Amount recovery (% of the applied dose) | |||
---|---|---|---|---|
Donor compartment | Newborn pig skin | Receptor compartment | Total | |
Ethosome | 84.65 ± 3.47a | 4.19 ± 0.17a | 1.17 ± 0.12a | 90.01 ± 3.59a |
Liposome | 87.51 ± 4.41a | 0.56 ± 0.05b | 0.41 ± 0.17b | 88.48 ± 4.29a |
PG solution | 84.09 ± 7.46a | 1.25 ± 0.23c | 1.31 ± 0.17a | 86.65 ± 7.33a |
30% hydroethanolic solution | 81.84 ± 8.86a | 2.27 ± 0.17d | 1.57 ± 0.15a | 85.69 ± 8.88a |
Data are expressed as % of total PR in the applied dose (0.5 mg/ml) (mean ± SEM, n = 5). a–d: means in the same column with different superscript letter differ significantly (P < 0.05).