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. 2017 Jul 19;2017:8310979. doi: 10.1155/2017/8310979

Table 3.

In vitro skin permeation parameters of PR following topical application of ethosome, liposome, 20% PG solution, and 30% hydroethanolic solution formulations.

Formulations J ss (µg/cm2/h) K p (×10−3 cm/h) T lag (h)
Ethosome 2.60 ± 0.27a 0.52 ± 0.05a 6 ± 0.63a
Liposome 0.96 ± 0.42b 0.19 ± 0.08b 7 ± 1.50a
PG solution 2.95 ± 0.42a,c 0.59 ± 0.08a,c 5 ± 0.49a
30% hydroethanolic solution 3.77 ± 0.31c 0.75 ± 0.06c 4 ± 0.40a

Each data represents the mean ± SEM (n = 5). Jss, steady state flux; Kp, permeability coefficient; Tlag, lag time. a–c: means in the same column with different superscript letter differ significantly (P < 0.05).