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. 2017 Aug 2;12(8):e0181585. doi: 10.1371/journal.pone.0181585

Fig 3. Selectivity profile of PKIS2 compounds using DiscoverX KINOMEscan.

Fig 3

Selectivity Index analysis of PKIS2. 357 compounds demonstrate an SI(65) of <0.04 at 1 μM, and thus inhibit less than 4% of the kinases in this screening panel with more than 65% inhibition at the 1 μM screening concentration.