Table 2.
Principal outcome measures in patients with ulcer bleeding according to treatment
|
No of patients
|
Pooled rates (%)
|
|||||||
|---|---|---|---|---|---|---|---|---|
| Outcome at 30 days after randomisation | No of trials | Proton pump inhibitor | Control | Heterogeneity (P value) | Proton pump inhibitor | Control | Odds ratio (95% CI) | Number needed to treat (95% CI) |
| Mortality | 18 | 1371 | 1403 | No (0.26) | 5.2 | 4.6 | 1.11 (0.79 to 1.57) | Not calculable |
| Rebleeding | 19 | 1408 | 1423 | Yes (0.05) | 10.6 | 18.7 | 0.46 (0.33 to 0.64) | 12 (8 to 25) |
| Surgical intervention | 17 | 1305 | 1336 | No (0.42) | 8.4 | 13.0 | 0.59 (0.46 to 0.76) | 20 (14 to 50) |