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. 2017 Aug 1;10:369. doi: 10.1186/s13071-017-2308-0

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Silencing of STAT-A abrogates late-phase immunity in the TEP1 mutant line. Midgut oocyst numbers were examined at day 2 and day 8 following P. berghei infection in the TEP1 mutant line after either injection of dsGFP (control) or dsSTAT-A. A significant reduction in oocyst numbers occurs between day 2 and day 8 for the control, while silencing of STAT-A impairs the effects of late-phase immunity on oocysts survival. Oocyst numbers were analyzed using Kruskal-Wallis with a Dunn’s post-hoc test. Asterisks denote significance (*P < 0.05, **P < 0.01). Abbreviation: ns, not significant