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. 2017 Aug 2;13(8):e1006527. doi: 10.1371/journal.ppat.1006527

Fig 8. B. abortus RNA degradation products are also able to retain MHC-I within the Golgi apparatus.

Fig 8

(A) Confocal micrographs of THP-1 cells treated with B. abortus RNA or RNase I-treated B. abortus RNA in the presence of IFN-γ for 48 h. MHC-I expression was determined with a primary anti-human MHC-I Ab (W6/32) and Alexa 546-labelled secondary Ab (red). Golgi apparatus was detected using a mAb specific for GM130 followed by Alexa 488-labelled secondary Ab (green). White arrows show co-localization (yellow staining). Cells treated only with RNase I were used as negative controls. Results are representative of three independent experiments.