Table 1.
Study place and period, birth population, cases (including pregnancy terminations), and rates of neural tube defects
|
Births
|
Cases
|
|||||
|---|---|---|---|---|---|---|
| Area | Coverage | Period | Total | Yearly* | No | Rate† |
| Norway | National | 1988-98 | 662 441 | 60 222 | 500 | 7.5 |
| Finland | National | 1988-98 | 697 687 | 63 426 | 537 | 7.7 |
| Northern Netherlands | Regional (three provinces) | 1988-98 | 205 653 | 18 696 | 196 | 9.5 |
| England and Wales | National (England and Wales) | 1988-98 | 7 424 798 | 674 982 | 4969 | 6.7 |
| Ireland | Regional (three counties, east Ireland) | 1988-98 | 209 997 | 19 091 | 240 | 11.4 |
| France, Paris | City (Greater Paris area) | 1988-98 | 406 140 | 36 922 | 404 | 9.9 |
| France, Strasbourg | City and surrounding area (Bas-Rhin) | 1988-97 | 134 063 | 13 406 | 114 | 8.5 |
| France, Central East | Regional | 1988-98 | 1 118 707 | 101 701 | 657 | 5.9 |
| Hungary | National | 1988-98 | 1 275 779 | 115 980 | 611 | 4.8 |
| Italy, Emilia Romagna | Regional (northern Italy) | 1988-98 | 271 494 | 24 681 | 100 | 3.7 |
| Italy, Campania | Regional (southern Italy) | 1991-8 | 351 166 | 43 896 | 234 | 6.7 |
| Portugal | Regional (three areas) | 1991-8 | 79 249 | 9 906 | 50 | 6.3 |
| Israel | Central area (three hospitals) | 1988-98 | 188 328 | 17 121 | 24 | 1.3 |
| Total | 13 025 502 | 1 200 030 | 8636 | 6.6 | ||
*
Average over study period.
†
Rate per 10 000 births.