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. 2017 Aug 1;13:35. doi: 10.1186/s13223-017-0207-8

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Immunohistochemistry of ITLN-1 expression in airway tissue. Representative distal BECs of SN-Asthma (a, b), and ST-Asthma (c, d) samples were stained with anti-ITLN-1 antibody (a, c) and IgG isotype control (b, d). The fields are 200 magnificent and antibodies are 1:500 diluted, respectively. ITLN-1 staining is mainly in the goblet cells in SN-Asthma. e ITLN-1 mRNA expressions before and after ICS (MF) treatment from 3 patients with 6 samples. Closed markers represent distal BECs and open markers are proximal BECs. Circles, triangles and squares are represented subjects individually. Additional small tables shows ITLN-1 mRNA values pre and post ICS treatments. Comparisons were done using the Wilcoxon test