Table I.

Cytokine concentrations in the peritoneum at 6 and 24 h post-CLP

Cytokines	Peritoneal Cavity (ng/ml)
	6 h		24 h
	Live-P	Die-P	Live-P	Die-P
Proinflammatory
IL-1β	2.0 ± 0.4	2.5 ± 0.3b	1.7 ± 0.2	2.2 ± 0.2
IL-2	0.25 ± 0.06	0.28 ± 0.04	0.66 ± 0.1a,c	0.45 ± 0.09
IL-6	98.2 ± 42.3a	250.9 ± 79.2	5.8 ± 0.7a	47.2 ± 11.6a
IL-12	0.8 ± 0.1	1.1 ± 0.1b	0.6 ± 0.1	0.9 ± 0.1b
IL-17	0.44 ± 0.08a	0.72 ± 0.11	0.29 ± 0.03a	0.37 ± 0.03a
IFN-γ	1.4 ± 0.2	1.8 ± 0.4	0.9 ± 0.1	3.4 ± 1.7b
CCL3 (MIP-1α)	11.1 ± 1.9	16.2 ± 1.9	9.2 ± 1.3	43.8 ± 14.4a−c
CCL2 (MCP-1)	60.8 ± 16.4a	119.8 ± 27.8	22.0 ± 2.9a	17.0 ± 3.8a
TNF-α	0.15 ± 0.03	0.26 ± 0.03b,c	0.11 ± 0.01	0.24 ± 0.03b,c
ICAM-1	6.5 ± 1.2	9.1 ± 1.4	7.0 ± 0.7	8.8 ± 0.9
Anti-inflammatory
IL-1ra	19.0 ± 3.2	22.5 ± 3.1	8.2 ± 0.8a,c	13.6 ± 1.6b,c
IL-4	1.6 ± 0.4	2.4 ± 0.4c	0.6 ± 0.1a,c	0.8 ± 0.1a,c
IL-10	7.5 ± 1.2	17.7 ± 3.2b,c	3.1 ± 0.8	16.0 ± 2.8b,c
TNF-srI	3.9 ± 0.7	6.0 ± 0.8b,c	3.3 ± 0.3	5.6 ± 0.5b,c
TNF-srII	27.0 ± 4.8	33.5 ± 4.4	16.0 ± 1.6a,c	20.6 ± 2.0a

Concentrations were calculated as described in Materials and Methods (at 6 h n = 9 for Live-P and 11 for Die-P; at 24 h n = 24 for Live-P and 13 for Die-P). Results are shown as mean ± SEM.

^ap < 0.05 when compared with Die-P at 6 h.

^bp < 0.05 when compared with Live-P at 24 h.

^cp < 0.05 when compared with Live-P at 6 h.