Table 3.
Serum Marker | Men (N=312)
|
Women (N=911)
|
|||||
---|---|---|---|---|---|---|---|
β | SE | P value | β | SE | P value | ||
Leptin (ng/mL) | Model Ib | 3.262 | 0.239 | <0.0001 | 2.923 | 0.117 | <0.0001 |
Model IIc | 3.209 | 0.244 | <0.0001 | 2.891 | 0.119 | <0.0001 | |
Adiponectin (μg/mL) | Model Ib | −0.328 | 0.256 | 0.21 | −1.113 | 0.120 | <0.0001 |
Model IIc | −0.308 | 0.261 | 0.24 | −1.085 | 0.122 | <0.0001 | |
C-reactive protein (mg/L) | Model Ib | 1.173 | 0.321 | 0.0003 | 1.579 | 0.125 | <0.0001 |
Model IIc | 1.179 | 0.328 | 0.0003 | 1.581 | 0.127 | <0.0001 | |
Tumor necrosis factor-α (pg/mL) | Model Ib | −0.901 | 0.468 | 0.06 | −0.039 | 0.214 | 0.86 |
Model IIc | −0.813 | 0.477 | 0.09 | −0.036 | 0.219 | 0.87 | |
Interleukin-6 (pg/mL) | Model Ib | 0.124 | 0.471 | 0.79 | 0.393 | 0.177 | 0.03 |
Model IIc | 0.176 | 0.470 | 0.71 | 0.377 | 0.180 | 0.04 |
Values are estimates from multivariable linear models; body mass index (BMI) and all serum biomarkers were log-transformed in all models.
Model I was adjusted for total energy intake at cohort entry (log-transformed, continuous), laboratory batch number (categorical), and month of blood draw [binary, winter (October–March) or non-winter (April–September) months].
Model II was further adjusted for red and processed meat intake at cohort entry (log-transformed, continuous).