Skip to main content
. Author manuscript; available in PMC: 2017 Aug 2.
Published in final edited form as: Nat Genet. 2016 Dec 19;49(2):269–273. doi: 10.1038/ng.3745

Figure 2. Genome-wide genetic correlation between PSC (and its subphenotypes), CD and UC.

Figure 2

Genetic correlations (and their 95% confidence intervals) were calculated using a bivariate extension of the linear mixed model30 implemented in GCTA (Online Methods). PSC has a lower genetic correlation with both CD and UC than the two inflammatory bowel diseases have to each other. PSC is genetically more correlated to UC than it is to CD and this is consistent across the PSC subphenotypes.