Table 4. Late clinical signs in LD.
| Clinical Signs at 3 or more years of disease | Mutation-positive (number and percentage) |
Gene test not performed (number and percentage) |
Total (number and percentage) |
|---|---|---|---|
| Reflex and spontaneous myoclonus | 13 (81.3%) | 11 (100%) | 24 (88.9%) |
| Hypnic myoclonus | 11 (68.8%) | 10 (90.9%) | 21 (77.8%) |
| Generalized tonic clonic seizures | 10 (62.5%) | 9 (81.8%) | 19 (70.4%) |
| Jaw Smacking | 7 (43.8%) | 5 (45.5%) | 12 (44.4%) |
| Fly Catching | 5 (31.3%) | 4 (36.4%) | 9 (33.3%) |
| Panic Attacks | 8 (50.0%) | 7 (63.6%) | 15 (55.6%) |
| Focal Seizures | 3 (18.8%) | 10 (90.9%) | 13 (48.1%) |
| Aggression toward people | 2 (12.5%) | 5 (45.5%) | 7 (25.9%) |
| Aggression toward dogs | 2 (12.5%) | 7 (63.6%) | 9 (33.3%) |
| Poor vision/blindness | 7 (43.8%) | 6 (54.5%) | 13 (48.1%) |
| Urinary Incontinence | 4 (25.0%) | 6 (54.5%) | 10 (37.0%) |
| Fecal incontinence | 3 (18.8%) | 5 (45.5%) | 8 (29.6%) |
| Dementia | 6 (37.5%) | 8 (72.7%) | 14 (51.9%) |
| Deafness | 4 (25.0%) | 4 (36.4%) | 8 (29.6%) |
Distribution of clinical signs in the LD affected and suspected dogs after 3 years of disease