Table 4.
Proteins involved in carbohydrate metabolism and transport identified in the midgut of Ornithodoros moubata females before feeding (unfed) and at 48 h post-feeding (fed). (T) Gene identified in the intestinal transcriptome of O. moubata [29]
| Experimental group | Database | UniProt ID | Protein | emPAI Unfed | emPAI Fed | Molecular function |
|---|---|---|---|---|---|---|
| Unfed | EST_Acari | B7PDB8 | 1,4-alpha-glucan branching enzyme | 0.62 | – | Transferase activity |
| Unfed | mRNA_Om | B7PDZ5 | Alpha-D-galactosidase (T) | 0.13 | – | Hydrolase activity |
| Unfed | EST_Acari | A0A0B1PR88 | Glucose-6-phosphate isomerase (T) | 0.35 | – | Isomerase activity |
| Unfed | mRNA_Om | E2C2M2 | Glucose transporter type 1 (T) | 0.08 | – | Carbohydrate transporter activity |
| Fed | mRNA_Om | A0A087UZ87 | ADP-dependent glucokinase (T) | – | 0.05 | Transferase activity |
| Fed | mRNA_Om | Q7Q4V0 | AGAP000862-PA (T) | – | 0.24 | Hydrolase activity |
| Fed | mRNA_Om | B7PE53 | Beta-hexosaminidase (T) | – | 0.1 | Hydrolase activity |
| Fed | mRNA_Om | G3MLS5 | Putative uncharacterized protein (T) | – | 0.65 | Hydrolase activity |
| Unfed-Fed | EST_Acari | B7P5Y3 | Alpha-1,4 glucan phosphorylase (T) | 1.74 | 0.1 | Transferase activity |
| Unfed-Fed | EST_Acari | B7QBK7 | Alpha-L-fucosidase (T) | 0.23 | 0.33 | Hydrolase activity |
| Unfed-Fed | mRNA_Om | A0A067R124 | Alpha-mannosidase (T) | 1.25 | 0.14 | Hydrolase activity |
| Unfed-Fed | mRNA_Om | B7PW84 | Beta-galactosidase (T) | 5.58 | 5.51 | Hydrolase activity |
| Unfed-Fed | mRNA_Om | A0A087TZD0 | Beta-hexosaminidase subunit alpha (T) | 0.85 | 0.69 | Hydrolase activity |
| Unfed-Fed | mRNA_Om | B7PL94 | Beta-mannosidase (T) | 0.13 | 0.09 | Hydrolase activity |
| Unfed-Fed | EST_Acari | B7PLL4 | Fructose-1,6-bisphosphatase | 1.95 | 1.22 | Hydrolase activity |
| Unfed-Fed | EST_Acari | E7F0E2 | Glucosamine-6-phosphate isomerase (T) | 0.98 | 0.98 | Isomerase activity |
| Unfed-Fed | mRNA_Om | B7PK21 | Glucosylceramidase (T) | 1.01 | 0.62 | Hydrolase activity |
| Unfed-Fed | mRNA_Om | A2V728 | Glutamine: fructose-6-phosphate aminotransferase (T) | 0.06 | 0.22 | Transferase activity |
| Unfed-Fed | EST_Acari | B7PLJ6 | Glycerol-3-phosphate dehydrogenase [NAD(+)] (T) | 0.57 | 0.57 | Oxidoreductase activity |
| Unfed-Fed | mRNA_Om | B7PH44 | Malate dehydrogenase (T) | 19.85 | 0.8 | Oxidoreductase activity |
| Unfed-Fed | mRNA_Om | B7QDE7 | Mannosyl-oligosaccharide glucosidase (T) | 0.27 | 0.23 | Hydrolase activity |
| Unfed-Fed | mRNA_Om | A9P774 | Phosphoenolpyruvate carboxykinase (T) | 8.58 | 0.33 | Kinase activity |
| Unfed-Fed | EST_Acari | A0A087UXS8 | Phosphoenolpyruvate carboxykinase [GTP], mitochondrial | 3.76 | 2.95 | Kinase activity |
| Unfed-Fed | mRNA_Om | A0A087TE96 | Poly(ADP-ribose) glycohydrolase ARH3(T) | 0.65 | 0.15 | Hydrolase activity |
| Unfed-Fed | mRNA_Om | G3MK74 | Putative uncharacterized protein (T) | 0.18 | 0.15 | Hydrolase activity |
| Unfed-Fed | mRNA_Om | B7Q5F0 | Transporter (T) | 0.08 | 0.08 | Carbohydrate transporter activity |
| Unfed-Fed | mRNA_Om | E9J2L5 | Putative uncharacterized protein (T) | 0.11 | 0.09 | Carbohydrate transporter activity |