Table 2. Thymocytes and BM from primary recipients of MSH2-/- BM induced lymphoma/T-leukemia in secondary recipients.

Donor Cell source	T-cell lymphoma/leukemia incidence	Latency (days)	Median Latency (days)
BM from primary recipients at weeks post transplantation
9 weeks	5/5	128–186	154
11 weeks	5/5	122–174	150
13 weeks	5/5	104–188	152
Thymocytes from primary recipients at weeks post transplantation
9 weeks	5/5	33–57	48
11 weeks	5/5	12–28	26
13 weeks	5/5	21–27	23

2x10⁶ MSH2-/- BM cells were transplanted into WT irradiated recipients. Thymus and BM from the primary recipients were harvested at 9, 11, and 13 weeks post transplantation (pooled from three mice each group), and 2x10⁶ BM cells or thymocytes were transplanted into sublethally irradiated WT secondary recipients (n = 5 per group). Lymphoma/leukemia development in the secondary recipients was monitored. Similar results were obtained in two independent experiments.