Table 4. CLIF-SOFA score according to history of HCC.

Area under the receiver operator characteristics (AUROC)
6-week mortality
Variable		Mortality rate (%)			AUROC		95% CI			P-value
All (n = 714)		13.1			0.943		0.917–0.968			<0.001
HCC (n = 146)		21.2			0.964		0.925–1.0			<0.001
Non-HCC (n = 568)		10.9			0.937		0.905–0.970			<0.001
Hospital mortality
Variable		Mortality rate			AUROC		95% CI			P-value
All		6.9			0.964		0.949–0.979			<0.001
HCC		8.9			0.956		0.923-.0990			<0.001
Non-HCC		6.2			0.965		0.947–0.983			<0.001
Cut-off points according to Youden index
6-week mortality
Predictive factors	Cut-off point		Youden index	Sensitivity (%)		Specificity (%)		PPV	NPV	Accuracy
CLIF-SOFA	6.5		0.758	0.871		0.887		0.536	0.979	0.885
HCC	6.5		0.834	0.903		0.930		0.778	0.973	0.924
Non-HCC	5.5		0.742	0.968		0.775		0.345	0.995	0.795
Hospital mortality
CLIF-SOFA	6.5		0.823	0.979		0.844		0.311	0.998	0.852
HCC	6.5		0.827	1.0		0.827		0.361	1.0	0.842
Non-HCC	6.5		0.819	0.971		0.848		0.296	0.998	0.856

CLIF-SOFA, chronic liver failure-sequential organ failure assessment; HCC, hepatocellular carcinoma