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Published in final edited form as: J Urol. 2011 Sep 25;186(5):1818–1824. doi: 10.1016/j.juro.2011.07.013

Prostate cancer in 52-year-old man. (a) Axial T2-weighted and ADC map of diffusion weighted (b) MR images demonstrate a low-signal-intensity lesion (arrow) in right mid anterior central gland lesion suspicious for cancer. K^trans (c) and k_ep (d) maps of dynamic contrast enhanced MRI localize tumor (arrow). MR spectroscopy (e) demonstrates increased ratio of choline (cho) to citrate (cit) in the right mid anterior central gland lesion (*) when compared with normal adjacent left side (+). Histopathologic slide (f) at mid prostate level confirms presence of tumor (Gleason score, 7) (black dotted line) detected on multi-parametric MRI (A = anterior, L = left, P = posterior, R = right).

Prostate cancer in 52-year-old man. (a) Axial T2-weighted and ADC map of diffusion weighted (b) MR images demonstrate a low-signal-intensity lesion (arrow) in right mid anterior central gland lesion suspicious for cancer. K^trans (c) and k_ep (d) maps of dynamic contrast enhanced MRI localize tumor (arrow). MR spectroscopy (e) demonstrates increased ratio of choline (cho) to citrate (cit) in the right mid anterior central gland lesion (*) when compared with normal adjacent left side (+). Histopathologic slide (f) at mid prostate level confirms presence of tumor (Gleason score, 7) (black dotted line) detected on multi-parametric MRI (A = anterior, L = left, P = posterior, R = right).