TABLE 1.

Definitions

Active TB disease	Either having evidence of a positive culture of Mycobacterium tuberculosis complex or clinical and/or radiological evidence of TB with clinician's decision to treat with a full course of anti-TB treatment Denotified cases or those with notification dates before their LTBI testing were excluded from analysis
Incident TB cases	Active cases notified >60 days after the LTBI test date We would expect cases detected through screening (prevalent TB cases) to be notified within this period, but tested this assumption with a sensitivity analysis varying the cut-off between 30 and 90 days
Prevalent TB cases	Active cases notified within 60 days of the screening date
LTBI	Either a positive TST or a positive IGRA (QuantiFERON-TB) test in the absence of active TB
	A positive TST required either a positive skin reaction Heaf grade 2–4 (equivalent to 6 mm Mantoux reaction) in the absence of prior BCG vaccination or a Heaf grade 3–4 (equivalent to 15 mm Mantoux reaction) for individuals with BCG vaccination

TB: tuberculosis; LTBI: latent TB infection; TST: tuberculin skin test; IGRA: interferon-γ release assay; BCG: bacille Calmette–Guerin.