Table 4. Probability threshold of decision curve analysis.
| Characteristic | Model | TCU (%) | Sensitivity | Specificity | PPV | NPV | LRP | LRN | NB | |
|---|---|---|---|---|---|---|---|---|---|---|
| All | Threshold | |||||||||
| OS (3 yr) | Kidd et al. [19] | 24 | 100 (100, 100) | 0 (0, 0) | 40 (26, 53) | - | 1.00 (1.00, 1.00) | - | 0.21 | 0.21 |
| NB all=NB threshold | ||||||||||
| 30 | 48 (26, 69) | 78 (64, 92) | 59 (35, 82) | 69 (54, 84) | 2.17 (0.98, 4.81) | 0.67 (0.43, 1.05) | 0.00 | 0.14 | ||
| NB all=NB none | ||||||||||
| 50 | 24 (6, 42) | 88 (79, 99) | 56 (23, 88) | 63 (49, 78) | 1.90 (0.58, 6.29) | 0.87 (0.66, 1.14) | −0.16 | 0.00 | ||
| NB none=NB threshold | ||||||||||
| DFS (1 yr) | Kidd et al. [19] | 24 | 38 (20, 57) | 79 (69, 89) | 42 (22, 61) | 77 (67, 87) | 1.84 (0.94, 3.61) | 0.78 (0.56, 1.08) | 0.06 | 0.06 |
| 25 | 35 (16, 53) | 81 (71, 90) | 41 (20, 61) | 76 (66, 86) | 1.78 (0.87, 3.66) | 0.81 (0.60, 1.10) | 0.04 | 0.05 | ||
| NB all=NB none | ||||||||||
| 32 | 19 (4, 34) | 84 (75, 92) | 31 (9, 54) | 73 (63, 83) | 1.17 (0.45, 3.04) | 0.97 (0.78, 1.20) | −0.06 | 0.00 | ||
| NB none=NB threshold | ||||||||||
| DFS (2 yr) | Rose et al. [20] | 19 | 99 (97, 100) | 3 (1, 6) | 33 (27, 39) | 86 (60, 100) | 1.02 (0.99, 1.06) | 0.35 (0.04, 2.84) | 0.16 | 0.16 |
| NB all=NB threshold | ||||||||||
| 33 | 82 (74, 90) | 42 (35, 50) | 41 (33, 48) | 83 (76;91) | 1.42 (1.21, 1.68) | 0.41 (0.25, 0.68) | 0.00 | 0.08 | ||
| NB all=NB none | ||||||||||
| 58 | 25 (16, 34) | 92 (87, 96) | 58 (42, 74) | 72 (66, 76) | 2.91 (1.59, 5.37) | 0.82 (0.72, 0.94) | −0.61 | 0.00 | ||
| NB none=NB threshold | ||||||||||
| Rd (5 yr) | Kang et al. [17] | 13 | 100 (100, 100) | 0 (0, 0) | 23 (17, 30) | - | 1.00 (1.00, 1.00) | - | 0.13 | 0.13 |
| NB all=NB threshold | ||||||||||
| 23 | 53 (37, 69) | 66 (58, 74) | 32 (21, 44) | 82 (74, 90) | 1.55 (1.05, 2.29) | 0.72 (0.50, 1.02) | 0.00 | 0.05 | ||
| NB all=NB none | ||||||||||
| 36 | 11 (1, 20) | 95 (91, 99) | 40 (10, 70) | 78 (71, 84) | 2.18 (0.65, 7.31) | 0.94 (0.84, 1.06) | −0.19 | 0.00 | ||
| NB none=NB threshold | ||||||||||
The cells show the estimate value and 95% CIs.
CI, confidence interval; DFS, disease-free survival; LRN, likelihood ratio negative; LRP, lihelihood ratio positive; NB, net benefit; NPV, negative predictive value; OS, overall survival; PPV, positive predictive value; Rd, distant recurrence; TCU, threshold of clinical utility.