Table 2.

Multivariate analysis testing the probability of pCR as a function of clinical-pathologic features and RPS

Variable	Odds Ratio (95%CI)	P-value
Clinical-pathologic factors
Age <50 years	1.37 (0.86–2.19)	0.18
Tumor stage 3, 4	0.63 (0.39–1.02)	0.058
Node positive	0.96 (0.58–1.60)	0.87
Grade 3	1.87 (1.04–3.43)	0.037
ER negative	3.49 (2.11–5.90)	<0.0001
HER2 positive	2.16 (1.16–3.97)	0.016
RPS value (per one unit decrease)	1.49 (1.10–2.02)	0.0091

Odds ratio of pCR determined using multivariate logistic regression analysis of the indicated covariates. Chi-square P-value determined using likelihood ratio test. ER=estrogen receptor; HER2=human epidermal growth factor receptor 2; CI=confidence interval.