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. Author manuscript; available in PMC: 2018 Aug 1.
Published in final edited form as: Clin Cancer Res. 2017 Apr 25;23(15):4010–4019. doi: 10.1158/1078-0432.CCR-17-0429

Figure 1. Literature search of all current pharmacogenomic anticancer chemotherapeutic induced toxicity GWAS.

Figure 1

Filters were designed to maximize initial results using PubMed [www.ncbi.nlm.nih.gov/pubmed] and the NHGRI-EBI GWAS Catalog [www.ebi.ac.uk/gwas/], followed by removing all candidate gene studies, studies of non-anticancer drugs, animal models, lymphoblastoid cell-line based GWAS and review articles. Numbers in blue boxes indicate initial query results; −338 indicates the studies that did not pass filtering criteria. The final result was 28 non-overlapping discovery studies with 17 studies including at least one replication set. Note: Search terms that yielded no results were excluded.