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. Author manuscript; available in PMC: 2018 Aug 1.
Published in final edited form as: Mol Cancer Res. 2017 May 8;15(8):1073–1084. doi: 10.1158/1541-7786.MCR-16-0424

Figure 1. Constitutive USP37 expression suppresses the growth of medulloblastoma cells in mouse orthotopic models.

Figure 1

DAOY cells were transiently transfected with plasmid pDEST26-Flag-HA-USP37 or a vector and implanted into mice cerebella (n=6 each). Animals were sacrificed and brains harvested for H&E staining. Scale bars = 50μM (left) and 100μm (right). The bar graph demonstrates the percentage of mice affected with tumor, vector (6/6) and USP37 WT (2/6). Wilcoxon-Rank Sum non-parametric analysis was performed to determine significance (*=p<0.05).