Figure 4. The effect of radium-223 treatment on visceral metastases in LuCaP 58 prostate cancer PDX model in mice.
The number of mice with visceral metastases in mice treated with 28 mmol/L sodium citrate as vehicle or with radium-223 (300 kBq/kg, i.v.). The bars represent all mice, mice with smaller (PSA < 5 ng/mL) and mice with larger (PSA > 5 ng/mL) amount of tumor growth. The numbers above the bars represent the number of mice with visceral metastasis per the number of mice in a respective group.