Table 5.
Heritability estimates for the AIs, their corresponding standard errors and P-values, based on a large family dataset (GOBS). In the middle part of the table are the genetic correlations between left and right volumes (heritabilities of their phenotypic correlations), and test P-values for whether the genetic correlations differ significantly from 0 and 1. In the right-hand part of the table are the environmental and phenotypic correlation estimates between left and right volumes
| Structure | AI heritability | Genetic correlation (ρ) between Left and Right | Phenotypic (ρ-phen) and environmental (ρ-env) correlation between Left and Right | ||||
|---|---|---|---|---|---|---|---|
| h2 (se) | P-value | ρ (se) | P (ρ = 0) | P (ρ = 1) | ρ-phen | ρ-env | |
| Nucleus accumbens | 0.114 (0.06) | 0.010 | 0.841 (0.07) | 4*10−10 | 0.003 | 0.54 | 0.34 |
| Amygdala | 0.040 (0.05) | 0.222 | 0.995 (0.03) | 8*10−24 | 0.424 | 0.71 | 0.39 |
| Caudate nucleus | 0.096 (0.06) | 0.053 | 0.974 (0.01) | 2*10−32 | 0.021 | 0.85 | 0.56 |
| Globus pallidus | 0.148 (0.06) | 0.002 | 0.823 (0.08) | 8*10−8 | 0.005 | 0.57 | 0.45 |
| Hippocampus | 0.180 (0.06) | 4*10−4 | 0.939 (0.02) | 2*10−25 | 7*10−4 | 0.78 | 0.53 |
| Putamen | 0.270 (0.07) | 8*10−7 | 0.899 (0.03) | 5*10−23 | 4*10−7 | 0.78 | 0.58 |
| Thalamus | 0.228 (0.06) | 2*10−5 | 0.824 (0.05) | 1*10−13 | 4*10−6 | 0.68 | 0.56 |