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. 2017 Feb 3;140(4):1004–1014.e13. doi: 10.1016/j.jaci.2016.12.963

Table E2.

Predominant cellular sources of biomolecules

Biomolecule Cellular source Biomolecule Cellular source
Innate immune cell–derived biomolecules Mixed cell–derived biomolecules
1. C3 M, DC 1. IL-1β Most cell types
2. CCL3 (MIP1β) M 2. IL-6 M, DC, Ep
3. CXCL7 (NAP2) P, M 3. IL-8 Ep, M, En, F, SM
4. Ficolin-3 M 4. Lipocalin 2 N, Ep
5. MMP9, total N 5. MMP7 N, Ep
6. PAI M, Ma, Ep
Airway tissue–derived biomolecules 7. SAA M, Ep
 1. Thrombospondin 1 F

DC, Dendritic cell; En, endothelial cell; Ep, epithelial cell; F, fibroblast; M, macrophage/monocyte; Ma, mast cell; MIP, macrophage inflammatory protein; N, neutrophil; P, platelet; PAI, plasminogen activator inhibitor; SM, smooth muscle.