Group differences in event-related activity between positive and threat trials. Shown in red, unique activation of right anterior MFG and anterior mPFC by the CA group compared to control group for threat trials. Also shown is unique activation of left caudate and right nucleus accumbens in the control group compared to CA group for positive trials. Lastly, greater suppression of vmPFC by the control group for threat than positive trials in contrast to greater suppression for positive than threat trials in the CA group is shown. Graph of percent signal change by group for a 5 mm sphere around the peak of two representative clusters, anterior MFG (44, 54, 6) and left caudate/right NA (− 8, 20, 2), are presented. MFG = anterior middle frontal gyrus. amPFC = anterior medial prefrontal cortex. NA = nucleus accumbens. vmPFC = ventral medial prefrontal cortex. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)