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. 2017 Aug 3;11:433. doi: 10.3389/fnins.2017.00433

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Copyright © 2017 Lehto, Albors, Sierra, Tolppanen, Eberly, Mangia, Nurmi, Michaeli and Gröhn.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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ROI analysis of MRI parameters in the dorsal tegmental tract, ipsilateral side. Mean and SD of RAFF4 (A), T_1sat (B), magnetization transfer ratio, MTR (C), fractional anisotropy, FA (D), mean diffusivity, MD (E), and axial and radial diffusivity, AD and RD (F,G) obtained from LPC induced lesion ROI in the dorsal tegmental tract of LPC injected (n = 6) rats and from the corresponding injection site ROI in vehicle injected (n = 4) rats. Statistical significance; ^* < 0.05 (FDR adj. for testing 7 MR parameters), Mann-Whitney U-Test.