Table 1.
Comparison of baseline characteristics between MCI patients and controls.
| Characteristic | MCI group (n = 124) | Control group (n = 102) | P |
|---|---|---|---|
| Age (years) | 62.46 ± 8.44 | 60.52 ± 7.98 | 0.079 |
| Female, n (%) | 63 (50.81) | 46 (45.10) | 0.393 |
| Education levels (years) | 8.30 ± 4.09 | 10.95 ± 3.46 | < 0.001 |
| Ever smoked, n (%) | 60 (48.39) | 41 (40.20) | 0.218 |
| Alcohol consumption, n (%) | 38 (30.65) | 36 (35.29) | 0.459 |
| Diabetes duration (years) | 10.35 ± 6.12 | 9.06 ± 4.89 | 0.085 |
| Hyperlipidemia (%) | 94 (75.81) | 64 (62.75) | 0.033 |
| BMI (kg/m2) | 25.08 ± 3.58 | 25.03 ± 3.34 | 0.909 |
| Hypertension, n (%) | 75 (60.48) | 59 (57.84) | 0.688 |
| SBP (mmHg) | 138.53 ± 18.60 | 133.66 ± 14.21 | 0.027 |
| DBP (mmHg) | 82.42 ± 10.94 | 81.40 ± 10.01 | 0.471 |
| HbA1c (%) | 9.54 ± 2.22 | 9.03 ± 2.34 | 0.105 |
| FBG(mmol/L) | 8.08 ± 2.73 | 7.66 ± 2.59 | 0.252 |
| TG (mmol/L) | 2.15 ± 1.99 | 2.08 ± 1.56 | 0.786 |
| TC (mmol/L) | 5.11 ± 1.55 | 4.69 ± 1.25 | 0.032 |
| HDL-c (mmol/L) | 1.20 ± 0.31 | 1.31 ± 0.25 | 0.003 |
| LDL-c (mmol/L) | 3.11 ± 0.88 | 2.98 ± 0.88 | 0.289 |
| apoA-I (g/L) | 1.07 ± 0.23 | 1.16 ± 0.26 | 0.021 |
| ApoB (g/L) | 0.82 (0.70–0.92) | 0.85 (0.69–1.02) | 0.373 |
| COGNITION TEST LEVELS | |||
| Global cognition | 21.00 (18.00–23.00) | 27.00 (26.00–28.00) | < 0.05 |
| Psychomotor speed | 81.00 (60.00–109.75) | 58.00 (47.75–71.00) | < 0.05 |
| Attention | 10.50 (8.00–12.00) | 12.00 (11.00–14.00) | < 0.05 |
| Executive function | 197.00 (150.00–273.25) | 142.50 (112.25–179.25) | < 0.05 |
| Verbal memory | 4.14 ± 2.39 | 7.13 ± 2.75 | < 0.05 |
| Logical memory | 5.04 ± 3.59 | 8.70 ± 3.61 | < 0.05 |
| Visual memory | 8.00 (7.00–10.00) | 16.00 (13.00–19.00) | < 0.05 |
Data are presented as n (%), mean ± SD, or median (interquartile range) as appropriate. Student's t-test, Mann-Whitney U-test, or × 2 test were used for comparison variables, MCI, mild cognitive impairment; BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; HbA1c, glycosylated hemoglobin; FBG, fasting blood-glucose; TG, triglyceride; TC, total cholesterol; HDL-c, high density lipoprotein cholesterol; LDL-c, low density lipoprotein cholesterol; apoA-I: apolipoprotein A1; ApoB: apolipoprotein B.