Table 4.
Distributions of ABCA1(R219K) genotype and allele frequencies in MCI and normal control with T2DM.
| Genotype and alleles | MCI, n (%) | Non-MCI, n (%) | Crude OR (95% CI) | P | Adjusted OR (95% CI)a | P |
|---|---|---|---|---|---|---|
| Overall | 124 | 102 | ||||
| R | 140 (56.45) | 123 (60.29) | 1.000 | |||
| K | 108 (43.55) | 81 (39.71) | 1.171 (0.804–1.707) | 0.410 | ||
| RR | 39 (31.45) | 37 (36.27) | 1.000 | 1.000 | ||
| RK | 62 (50.00) | 49 (48.04) | 1.200 (0.669–2.156) | 0.541 | 1.172 (0.626–2.196) | 0.620 |
| KK | 23 (18.55) | 16 (15.69) | 1.364 (0.625–2.977) | 0.435 | 1.103 (0.730–1.666) | 0.643 |
| RK + KK | 85 (68.55) | 65 (63.73) | 1.241 (0.713–2.158) | 0.445 | 1.081 (0.806–1.449) | 0.605 |
Data are presented as n (%).
×2 test was used to compare the genotype and allele frequencies.
a
Adjusted for age, education level, sex.
ABCA1, ATP-binding cassette transporter A1; MCI, mild cognitive impairment; T2DM, Type 2 diabetic mellitus.