Table 5.

Comparison of lipid levels according to ABCA1 R219K polymorphism.

Parameters	All group (n = 226)			P	MCI group (n = 124)			P	Control group(n = 102)			P
	RR	RK	KK		RR	RK	KK		RR	RK	KK
TG(mmol/L)	2.08 ± 1.44	2.02 ± 2.01	2.46 ± 1.84	0.426	2.05 ± 1.32	2.02 ± 2.28	2.49 ± 2.13	0.367	2.12 ± 1.57	2.03 ± 1.64	2.14 ± 1.35	0.953
TC(mmol/L)	4.94 ± 1.23	4.89 ± 1.59	4.94 ± 1.35	0.968	5.25 ± 1.36	5.05 ± 1.71	5.01 ± 1.42	0.782	4.61 ± 0.99	4.70 ± 1.41	4.86 ± 1.30	0.809
HDL(mmol/L)	1.19 ± 0.25	1.27 ± 0.31	1.30 ± 0.29	0.109	1.11 ± 0.25	1.22 ± 0.34	1.29 ± 0.26	0.055	1.29 ± 0.22	1.33 ± 0.24	1.31 ± 0.33	0.790
LDL(mmol/L)	3.11 ± 0.83	3.02 ± 0.96	3.01 ± 0.74	0.781	3.29 ± 0.89	3.03 ± 0.92	2.99 ± 0.71	0.276	2.91 ± 0.71	3.01 ± 1.01	3.04 ± 0.80	0.817
apoA-I (g/L)	1.06 ± 0.23	1.13 ± 0.26	1.16 ± 0.23	0.093	0.99 ± 0.17	1.11 ± 0.25	1.14 ± 0.24	0.021	1.14 ± 0.26	1.16 ± 0.26	1.17 ± 0.26	0.896
ApoB (g/L)	0.81(0.73–0.97)	0.82(0.67–0.95)	0.84(0.71–0.92)	0.921	0.80(0.72–1.01)	0.82(0.67–0.92)	0.80(0.70–0.92)	0.878	0.81(0.74–0.96)	0.86(0.65–1.05)	0.87(0.76–1.02)	0.891

Data are presented as mean ± SD or median (interquartile range) as appropriate.

One-way ANOVA for the comparison of the lipid levels between different genotypes of ABCA1.

ABCA1, ATP-binding cassette transporter A1; MCI: mild cognitive impairment; TG, triglyceride; TC, total cholesterol; HDL-c, high density lipoprotein cholesterol; LDL-c, low density lipoprotein cholesterol; apoA-I: apolipoprotein A1; ApoB: apolipoprotein B.