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. 2017 Aug 2;7:7118. doi: 10.1038/s41598-017-07216-6

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Effects of perinatal FM 550 exposure on juvenile behavior in the light dark box (L/D). No significant effect of sex was observed between control males and females for any of the L/D box measurements. In females, there was no significant effect of exposure for any of the observed endpoints. In males, latency to enter the light box was significantly reduced and light box entries were significantly increased at the highest dose (A and B), while no significant effect of exposure was observed for duration in the light box (C). White bars indicate control groups, light gray low dose, dark grey mid dose, and black high dose. Graphs depict mean ± SEM (*p ≤ 0.05).