Table 1. The composition of stabilizers used during lyophilization of the ERAGS strain.
Component | LPGG, g (mM) | TPGG, g (mM) |
---|---|---|
Lactose (C12H22O11) | 100 (292.2)a) | - |
Trehalose dehydrate (C12H22O11) | - | 100 (264.3) |
Monopotassium phosphate (KH2PO4) | 0.52 (3.8) | 0.52 (3.8) |
Potassium phosphate dibasic (K2HPO4) | 0.854 (4.85) | 0.854 (4.85) |
Monosodium L-glutamate (C5H8NNaO4) | 0.829 (4.9) | 10 (59.1) |
Sorbitol (C6H14O6) | - | 20 |
Gelatin | 5 | 5 |
LPGG, lactose/phosphate/glutamate/gelatin; TPGG, trehalose/phosphate/glutamate/gelatin.
a)The amounts are those required for lyophilization of 1 L of the vaccine.