Table 2.
Patient factors associated with willingness to switch to oral therapy on initial questionnaire.
| No. (%) of subjects | Unadjusted | Adjusted* | ||||
| Patient factor | Willing to switch n = 63 | Not willing to switch n = 23 | OR (95% CI) | p-value | OR (95% CI) | p-value |
| Time to clinic | ||||||
| 0–29 minutes | 49 (87) | 7 (13) | 9.34 | <0.001 | 9.29 | 0.003 |
| 30+ minutes | 12 (43) | 16 (57) | (3.14–27.78) | (2.16–39.97) | ||
| Perceived disadvantages of injections | ||||||
| Frequent visits to see MD/nurse | ||||||
| Agree | 38 (86) | 6 (14) | 4.31 | 0.010 | 5.41 | 0.038 |
| Disagree | 25 (60) | 17 (40) | (1.49–12.42) | (1.10–26.56) | ||
| Cost to health care system | ||||||
| Agree | 26 (93) | 2 (7) | 7.38 | 0.010 | 16.68 | 0.023 |
| Disagree | 37 (64) | 21 (36) | (1.59–34.23) | (1.51–184.22) | ||
* Adjusted for patient factors at least weakly associated (i.e., p < 0.20) with a willingness to switch to oral B12 therapy in bivariate analyses: gender, time to clinic, satisfaction with past B12 injections, perceived disadvantages of injections (shots are painful, frequent visits to see MD/nurse, cost to health care system), perceived disadvantage of pills (won't see MD/nurse as often)